Synthesis, Characterization and Biological Activity of New Amides Containing Azo Moieties

Bin Selim, Elham Abdalrahem and Hadi Al–Douh, Mohammed and Bin Mahram, Samia Mabrook and Al–Haik, Wedad Mohammed and Sonbol, Khalid Saeed (2022) Synthesis, Characterization and Biological Activity of New Amides Containing Azo Moieties. Asian Journal of Applied Chemistry Research, 11 (2). pp. 11-22. ISSN 2582-0273

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Official URL: https://doi.org/10.9734/ajacr/2022/v11i230250

Abstract

Three new amide compounds 6, 8 and 9 were derived from diazo dye 4. 4-Hydroxy-3-methoxy-5-(2,6-dinitrophenyl) benzaldehyde 4 was reacted separately with compounds 5 and 7 to obtain 6 and 8, respectively. The amide compound 9 was synthesized by two different methods. The reaction between 6 and a diacyl chloride compound 7 gave compound 9. Also, compound 9 was produced via the reaction of compound 8 and an N-terminus compound 5. All compounds were characterized by their melting points, UV-Vis, and FTIR spectra. Moreover, the mass spectrum and elemental analysis of compound 9 were determined. All three synthesized compounds were tested against P. mirabilis, E. coli, and S. aureus at different concentrations and showed significant results.

Item Type:	Article
Subjects:	EP Archives > Chemical Science
Depositing User:	Managing Editor
Date Deposited:	14 Feb 2023 06:38
Last Modified:	22 Jun 2024 07:58
URI:	http://research.send4journal.com/id/eprint/1237

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