A RANDOMIZED CONTROLLED TRIAL OF ORAL NIFEDIPINE AND PARAENTRAL ISOXSUPRINE IN ARRESTING PRETERM LABOUR

In our study the success rate of Isoxsuprine was slightly more as compared to Nifedipine group but the maternal and foetal side effects were more in Isoxsuprine group. Nifedipine is better tolerated drug as compared to Isoxsuprine. Study involved 80 patients with the diagnosis of preterm labour with the gestational age of 28-36 weeks. 40 were assigned to Nifedipine and 40 to Isoxsuprine group. Drugs were administrated according to protocol. Patients were followed up till delivery and outcome parameters measured. Preterm labour was found to be more common in women from rural area and with low socioeconomic status.