Possible Risk Associations for the Formation of Antisperm Antibodies: A Review

Research has shown the negative effects of antisperm antibodies (ASA) on the infertility. However, the precise etiology of the formation of ASA is yet to be established. Many researchers have suggested possible risk factors for ASA formation while others have contradictory findings. This article reviews the recent published literature in English language using MEDLINE, Google Scholar and print journals to identify the risk associations for ASA formation in human. Collated research findings do not strongly prove associations between ASA and possible risk factors. This, to some extent reflects the inadequacy of well-designed and case controlled studies in this regard.