An Assessment of Hepato-Protective Activity of Psidium guajava Fruit Extract against Hepatic Injured Rodent Model

Md., Abdullah Hil Baky Rupak and F. M., Sharifuzzaman Shohan and Juliana, Aditi Baroi and Md., Rahmat Ullah and Md., Mustafiz Chowdhury and Bornila, Mehjabin and Puja, Bhowmik and Nur-Neasha, Dolon and Rafat, Tashin (2023) An Assessment of Hepato-Protective Activity of Psidium guajava Fruit Extract against Hepatic Injured Rodent Model. Asian Journal of Medical Principles and Clinical Practice, 6 (2). pp. 240-245.

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Abstract

Herbal remedies are the art or practice of using herbs and herbal medicines to maintain health and prevent, treat, or cure sickness. The lipid profiles of Psidium guajava extract were studied in rats. In the case of Serum glutamic pyruvic transaminase (SGPT) and serum glutamic-oxaloacetic transaminase (SGOT), only the high dose produced statistically significant (p<0.05) outcomes as compared to the negative control group. At low, medium, and high dosages, creatinine levels decreased statistically significant (p<0.05). However, none of the dosages in case of urea produced statistically significant (p<0.05) effects. Only at high dosages did total cholesterol levels reduce statistically significantly (p<0.05) when compared to the negative control group. Only at high doses did High Density Lipoprotein (HDL) levels improve statistically significantly (p<0.05). High and medium dosages of Low Density Lipoprotein (LDL) significantly (p<0.05) reduce the quantity in the blood. Triglyceride levels were reduced only at high dosages as compared to the negative control group. These discoveries may benefit those suffering from liver disorder.

Item Type: Article
Subjects: EP Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 09 Oct 2023 06:22
Last Modified: 09 Oct 2023 06:22
URI: http://research.send4journal.com/id/eprint/2844

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