SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW COUMARIN, PYRIDINE, 1,2,3-TRIAZOLE, THIAZOLIDINONE, PYRAZOLOTRIAZINE, THIOPHENE AND THIAZOLE DERIVATIVES BEARING CARBONYLHYDRAZONOETHYLPHENYLTOSYLATE MOIETY

ABDELALL, MAHMOUD M. and MOHAMED, SHABAN I. and HALAWA, AHMED H. and HASSAN, AHMED A. (2011) SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW COUMARIN, PYRIDINE, 1,2,3-TRIAZOLE, THIAZOLIDINONE, PYRAZOLOTRIAZINE, THIOPHENE AND THIAZOLE DERIVATIVES BEARING CARBONYLHYDRAZONOETHYLPHENYLTOSYLATE MOIETY. Al-Azhar Bulletin of Science, 22 (2). pp. 165-180. ISSN 1110-2535

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Abstract

A number of novel coumarin (4), pyridinone (5a,b), thiophenopyridinone (6), 1,2,3-triazole (7), pyrazolotriazine (10), thiazole (11,14a,b,15), thiophene (12), thiazolidinone (20,21,23) derivatives were synthesized via interaction of 4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyltosylate (3) with different nucleophilic reagents. The structures of the newly synthesized compounds were confirmed by elemental analyses IR, 1H-NMR and mass spectral data. All compounds were evaluated for their antimicrobial activities.

Item Type: Article
Subjects: EP Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 16 Sep 2023 05:13
Last Modified: 16 Sep 2023 05:13
URI: http://research.send4journal.com/id/eprint/2538

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